If a study plans from the outset to collect data in a way that is comparable to how it was collected in an earlier sweep, or by a different study, this is called ‘prospective harmonisation’. In order to sufficiently prepare for future data harmonisation, documentation from previous studies can be important to understanding details related to the assessment methods that were used.
Prospective harmonisation is not without its own challenges. It can restrict studies from using more novel assessment methods or approaches customised to their specific research question or characteristics of their sample. However, prospective harmonisation does not have to mean asking exactly the same questions of participants or running all of the same tests but only those for which comparison or data pooling is planned. Moreover, they may not have to be exactly identical. Sometimes it is possible to use slightly different assessments if there is a statistical basis for calibrating the different measures. For example, researchers have produced algorithms for adjusting measures captured by older types of blood pressure monitor to make them more comparable to blood pressure values produced by newer devices).
As documentation is at the heart of all forms of harmonisation, metadata concepts and standards play a key role. To learn more about what metadata means and why standardised documentation methods are helpful to cross-study and cross-sweep research, see Understanding Metadata.
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