In the case of some longitudinal studies, the target population is much larger than the desired number of participants so a smaller subsample needs to be selected. Study teams use various methods to make sure that this subsample is as representative of the target population as possible. These sampling methods have become more sophisticated over time as sampling methods have evolved.
For example, the first three British birth cohorts selected their sample of births by choosing a specific week within the relevant year (1946, 1958 and 1970). All births within those weeks were eligible to be included in the first round of each study. The 1958 and 1970 birth cohorts included these participants in subsequent waves of the study; in the case of the 1946 birth cohort, a subsample of cases from the first study were followed up.
There were several limitations to this approach. In particular, the sample is potentially not representative of everyone born in that year – only of those born in that season. This makes it is impossible to use the data to explore issues like whether season of birth affects later outcomes, such as educational attainment.
This is one of the reasons that the most recent birth cohort, the Millennium Cohort Study, selected its sample of births from across a whole school year. This allows researchers to be confident that the data collected can be used to make inferences about the wider population born at the turn of the century.
However, it is important to be aware that there is a debate within epidemiology about whether the importance of having representative samples drawn from well-defined populations has been overrated. Instead, it is argued, some research questions are better addressed by sample designs that focus upon particular groups of interest rather by seeking to obtain a representative sample of the relevant population as a whole. For an introduction to this discussion see this article in the Longitudinal and Life Course Studies journal.
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